So, as you may know already, I have decided to pursue a detox program in fighting my cancer. In, Part 1 of This Post – Detox – The Forest from the Trees, I talked about the confusion surrounding the whole detox subject and my decision to redefine the problem. In doing so, I feel less lost and more in control. I have decided to create something that I am calling my detox. It’s just my own program instead of following some detox program designed by somebody else. After all, they don’t know me and they don’t know my health issues. Also, because carcinoid tumors are so rare there is no standard “regimen” to fight them (natural or otherwise). If you are a patient with carcinoid tumors then you already know that there is no standard “protocol”, as far as I know, to fight it. So, I am following my doctor’s advice but pursuing a healthier lifestyle with vigor. I invite you to start building your own detox program with me. I look forward to hearing any suggestions that you might have.
My detox is not just a detox program but also a program to build up my immune system and overall health. So, it includes both positive and negative properties. First let me address the negative or, the elimination of unhealthy elements. I will address the positive, oxygenating aspects, of weight loss and exercise in a later post.
Weight Loss – Obesity is a cancer causing factor and so, the more fit you are the better your chances. Here’s a short video that shows the link between obesity and cancer.
Here’s some added information from the National Cancer Institute.
One study, using NCI Surveillance, Epidemiology, and End Results (SEER) data, estimated that in 2007 in the United States, about 34,000 new cases of cancer in men (4 percent) and 50,500 in women (7 percent) were due to obesity. The percentage of cases attributed to obesity varied widely for different cancer types but was as high as 40 percent for some cancers, particularly endometrial cancer and esophageal adenocarcinoma.
The article goes on to explain that there are several mechanisms that have been suggested to explain the link between excess weight and cancer. One is that fat tissue produces excess amounts of estrogen and has been associated with the risk of breast, endometrial and other cancers. Are you thinking endocrine system? You should be. Read More Here
The endocrine system controls maturation, development, growth, and regulation within the body. It consists of glands (such as the pituitary, the pancreas, the adrenals, and the testes) and hormones, which are natural chemical messengers. The endocrine glands secrete carefully measured amounts of these messenger chemicals into the bloodstream. They travel to different parts of the body and bind to specific receptors in order to control and adjust many life functions. For example, estrogen is a hormone secreted primarily by the ovaries. It controls the menstrual cycle, fertility, and maintenance of a healthy pregnancy, among other critical activities in adults. In the fetus, estrogen is essential for normal development of both males and females. Read More at the Natural Resources Defense Council
In addition, obese people often have increased levels of insulin and insulin-like growth factor-1 (IGF-1) in their blood (a condition known insulin resistance or hyperinsulinemia), which may promote the development of certain tumors. My doctor told me that Neuroendocrine tumors might be lumped into this group and I wouldn’t be surprised since we are talking about the endocrine system again. Are you starting to see a pattern? I am. I think it’s time to really focus on the endocrine system and detoxing with that in mind don’t you?
In addition, obesity often leads to chronic low-level inflammation which has also been linked to cancer. Not to mention more hormonal issues called adipokines which may stimulate or inhibit cell proliferation. Whenever I hear hormones I think endocrine system. Leptin, which is more abundant in obese people, seems to promote cell proliferation, whereas adiponectin, which is less abundant in obese people, may have antiproliferative effects. Translation….metastases.
Fat cells may also have direct and indirect effects on other tumor growth regulators, including mammalian target of rapamycin (mTOR). mTOR is a protein that helps control several cell functions, including cell division and survival. Blocking mammalian target of rapamycin may cause the cancer cells to die. It is a type of serine/threonine protein kinase.
Rapamycin is a drug used to keep the body from rejecting organ and bone marrow transplants. Rapamycin blocks certain white blood cells that can reject foreign tissues and organs. It also blocks a protein that is involved in cell division. It is a type of antibiotic, a type of immunosuppressant, and a type of serine/threonine kinase inhibitor. Rapamycin is now called sirolimus.
Kinase is a type of enzyme (a protein that speeds up chemical reactions in the body) that adds chemicals called phosphates to other molecules, such as sugars or proteins. This may cause other molecules in the cell to become either active or inactive. Kinases are a part of many cell processes. Some cancer treatments target certain kinases that are linked to cancer. (This came from the Same Link at NCI.)
If you would like to read more about how these tumor growth regulators control the cancer cell then here’s a quote from another article to wet your appetite from Sci-News.com.
“We have discovered that a cellular component, eEF2K (eukaryotic elongation factor 2 kinase), plays a critical role in allowing cancer cells to survive nutrient starvation, whilst normal, healthy cells do not usually require eEF2K in order to survive. Therefore, by blocking the function of eEF2K, we should be able to kill cancer cells, without harming normal, healthy cells in the process.” Read More Here
They are using these very substances to kill the cancer so…if losing weight will do the same thing even to a small degree then let’s start there. You can read the reference article here. When reading the reference article, if you click on “paperclip” on the right near the picture then you can even listen to the interview or you can Download It Here and listen at your leisure.
So, step one on “My Detox” program is to lose the fat. I plan to exercise moderately as I am very fatigued and use a meal replacement (juice I think) to lower my caloric intake. Feel free to join me and comment. Yes, I will be researching eEF2K. 🙂
I will keep you updated,