Yes, you read that correctly. I try to stay on top of things such as new meds, techniques, therapies and such in my cancer fight. As it turns out, it looks like we may have a reason to hope. They have found a way to dissolve the protein that keeps our immune system from attacking the cancer. Here’s a quote from the Stanford School of Medicine.
Stanford researchers have previously shown that CD47, a molecule found on the surface of many cancers, acts as a “don’t eat me” signal that protects the cancer from roving immune cells called macrophages. The scientists found that when they used drugs to block this “don’t eat me” signal, macrophages engulfed and destroyed the cancer cells. Read More
I read further and they implanted cancer in mice and the cancers just “melted away” when the mouse was given anti-cd47 antibodies. It seems that CD47 is a protein found on all cancer cells. Here’s a video you should find interesting.
Have they found a Cure for Cancer
So, are we going to see a cure for all cancers? Well, I have to be honest, I have high hopes for this treatment. I read that we may see it commercially available within 5 years but, I think that is optimistic. I HOPE that we will not see the FDA block a potential cure. They have stood in the way of many useful technologies and medicines that have been proven to be useful in the fight against cancer. Just take a look at the long road Gallium 68 has had to travel just to be used in clinical trials. Gallium 68 is a standard in almost every other country but not here in America. It’s a shame because it offers a much more accurate scan for carcinoid cancer patients.
The use of anti-CD47 Antibodies in treating cancer is so promising that they are talking about a future cancer vaccine. Here’s another quote for you.
The fact that T cells become involved in fighting cancer as a result of CD47-blocking antibody therapy could have important clinical implications. The antibody might be used as a personalized cancer vaccine allowing T cells to recognize the unique molecular markers on an individual patient’s cancer. “Because T cells are sensitized to attack a patient’s particular cancer, the administration of CD47-blocking antibodies in a sense could act as a personalized vaccination against that cancer,” Tseng added. Read More
As promising as this treatment seems there are limitations. It seems that if there is a lot of cancer then this does treatment is not as effective. The good news is that doctors are already thinking of ways to shrink the amount of tumors in the body so that they can use this treatment to fight cancer.
The anti-CD47 antibody presents a novel way of combatting cancer however it is not without limitations. The success of obliterating cancer is dependent on the volume of the tumour. Combination treatments are beginning to be explored but the replacement of radiotherapy and chemotherapy is much preferred to reduce adverse effects on normal cells. The increased concentration of in situ macrophages would perhaps offer a better solution to eliminate bigger and more aggresive tumours. Read More
So, this is the new focus of my personal research. Do carcinoid tumors have this CD47 protein? I expect so. I will be looking into this further. Also, what are the actual antibody names and compounds that dissolve these compounds? I’ll keep hoping for a cure from my oncologist, eating organic and taking supplements that make me healthier. I’m staying positive and looking for my own answers as well. If you know anything about anti-cd47 therapies please let me know.
Stay Strong and Keep Fighting,
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