I have finally have a plan to fight my cancer. My doctor has put me on Xeloda, which is the commercial name for capecitabine. You can read that post about Xeloda here. I was so hopeful that it would work but, unfortunately it didn’t. The tumors in my liver have grown more although it did seems to have stabilized some of the other tumors in my body. It did relieve a lot of the symptoms that I was having because of the cancer. The doctor says that this is probably because the swelling in my lymph nodes has gone down. This round of chemo was pretty rough and I think it’s about to get tougher. Anyway, my carcinoid cancer treatment is on to plan b. Plan B is Xeloda AND Temodar or Capecitabine and Temozolomide (CAPTEM). I think that CAPTEM is an actual drug and not just the 2 drugs used together so I don’t think I am technically on CAPTEM because my doctor has prescribed them separately.
I have been having quite a hard time finding a doctor that I felt was a good match for me. Well, it seems that things may have finally worked out for me because, as you know from previous post “I finally have a plan to fight my cancer”,my current doctor seems to be a much better fit for me.
So, back to CAPTEM. There’s a great video that you can watch. It’s very recent and discusses a recent phase II clinical trial that ended and how promising the results were. Check it out. It looks very promising! 95% of the carcinoid patients were helped in some way. Take a look!
It seems that both Xeloda and Temodar both work on the same principles They both stop the cancer cells from dividing. Here’s some information on Temodar from the American Cancer Society.
Temozolomide belongs to a group of chemotherapy drugs called alkylating agents. Unlike many other chemotherapy drugs, it can reach the brain from the bloodstream. It slows or stops the growth of cancer cells, which causes them to die. Read More
Here’s a bit more from Wikipedia. It’s a bit technical but, you can glean a lot from the article.
The therapeutic benefit of temozolomide….damages the DNA and triggers the death of tumor cells. However, some tumor cells are able to repair this type of DNA damage, and therefore diminish the therapeutic efficacy of temozolomide, by expressing a proteinO6-alkylguanine DNA alkyltransferase (AGT) encoded in humans by the O-6-methylguanine-DNA methyltransferase (MGMT) gene. In some tumors, epigenetic silencing of the MGMT gene prevents the synthesis of this enzyme, and as a consequence such tumors are more sensitive to killing by temozolomide. Read More
I’ve been warned the the Temodar will cause nausea and I’ve been given anti-nausea meds to go with it. As you might have guessed by now, I am hoping this will work for me. If you think of it would you please say a prayer for me and my family. We’re such a happy family and love each other so much. My son is only 6 and I want to be there for him. I would be so thankful if you did that.
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